Open access

Papers, explained

338 open-access papers, free to watch.

Sweet spot in music—Is predictability preferred among persons with psychotic-like experiences or autistic traits? 4:56

Sweet spot in music—Is predictability preferred among persons with psychotic-like experiences or autistic traits?

Why can one person love a song that feels safely familiar while another finds it unbearably dull? This study found that music’s sweet spot really does move from person to person, but not for the reasons researchers expected.

Atherosclerosis treatment with nanoagent: potential targets, stimulus signals and drug delivery mechanisms 6:42

Atherosclerosis treatment with nanoagent: potential targets, stimulus signals and drug delivery mechanisms

Heart disease kills at least nearly one in three people worldwide, yet the drugs used to fight artery disease can miss the damaged area or harm other organs. This review explores a striking alternative: tiny carriers that may find the trouble and open their medicine there.

Prescriptions of homeopathic remedies at the expense of the German statutory health insurance from 1985 to 2021: scientific, legal and pharmacoeconomic analysis 5:10

Prescriptions of homeopathic remedies at the expense of the German statutory health insurance from 1985 to 2021: scientific, legal and pharmacoeconomic analysis

When public health insurance pays for a treatment, the question is not only whether people want it. It is whether the evidence, the price, and the safety information justify using everyone’s shared money.

Exploitation of Quercetin’s Antioxidative Properties in Potential Alternative Therapeutic Options for Neurodegenerative Diseases 3:14

Exploitation of Quercetin’s Antioxidative Properties in Potential Alternative Therapeutic Options for Neurodegenerative Diseases

A compound found in fruits and vegetables may help protect nerve cells from damage linked to aging brain diseases. But the evidence is promising, uneven, and not yet a treatment people can rely on.

Methodological issues of the electronic health records’ use in the context of epidemiological investigations, in light of missing data: a review of the recent literature 3:12

Methodological issues of the electronic health records’ use in the context of epidemiological investigations, in light of missing data: a review of the recent literature

Medical records can help prevent disease and improve treatment, even when parts of a patient’s story are missing. But the way those blank spaces are handled can quietly change the conclusion doctors and researchers reach.

Machine Learning Interatomic Potential for Modeling the Mechanical and Thermal Properties of Naphthyl-Based Nanotubes 3:20

Machine Learning Interatomic Potential for Modeling the Mechanical and Thermal Properties of Naphthyl-Based Nanotubes

A tiny carbon structure can stay intact at temperatures far beyond ordinary industrial heat, yet snap suddenly when stretched. This study builds a faster way to find out exactly where those limits lie.

2023 European Kidney Forum: The future of kidney care – investing in green nephrology to meet the European Green Deal targets 3:56

2023 European Kidney Forum: The future of kidney care – investing in green nephrology to meet the European Green Deal targets

Kidney care can save lives while adding to pollution, waste, and heavy resource use. This paper argues that the treatment keeping people alive also needs a climate plan.

Stromal cells engineered to express T cell factors induce robust CLL cell proliferation in vitro and in PDX co-transplantations allowing the identification of RAF inhibitors as anti-proliferative drugs 4:33

Stromal cells engineered to express T cell factors induce robust CLL cell proliferation in vitro and in PDX co-transplantations allowing the identification of RAF inhibitors as anti-proliferative drugs

Chronic leukemia cells often stop growing when removed from the body, making them hard to study. This study rebuilt the neighborhood around them, and made their hidden growth behavior visible, then found a drug class that stopped it.

Marine monitoring based on triboelectric nanogenerator: Ocean energy harvesting and sensing 4:36

Marine monitoring based on triboelectric nanogenerator: Ocean energy harvesting and sensing

The ocean is full of motion, but measuring it usually means sending power to equipment in a difficult place. This paper explores devices that turn the ocean’s own movement into both electricity and information.

The transcription factor CsS40 negatively regulates TCS1 expression and caffeine biosynthesis in connection to leaf senescence in Camellia sinensis 3:16

The transcription factor CsS40 negatively regulates TCS1 expression and caffeine biosynthesis in connection to leaf senescence in Camellia sinensis

As tea leaves grow older, they make less caffeine, and this study points to a biological switch that may connect caffeine loss with the leaf’s aging process.

Fire and ant interactions mediated by honeydew and extrafloral nectar in an australian tropical savanna 4:03

Fire and ant interactions mediated by honeydew and extrafloral nectar in an australian tropical savanna

Fire usually sounds like a force that breaks relationships in nature. But in this Australian savanna, frequent burning helped plants and ants connect more often, and brought more of the most protective ants into the picture.

Alteration of the N6-methyladenosine methylation landscape in a mouse model of polycystic ovary syndrome 4:26

Alteration of the N6-methyladenosine methylation landscape in a mouse model of polycystic ovary syndrome

Polycystic ovary syndrome can affect periods, fertility, and long-term health, yet there is no single treatment for its underlying cause. This study points to a tiny chemical mark on genetic messages as one possible piece of the puzzle.