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338 open-access papers, free to watch.

Specific Detection of Physiological S129 Phosphorylated α-Synuclein in Tissue Using Proximity Ligation Assay 4:06

Specific Detection of Physiological S129 Phosphorylated α-Synuclein in Tissue Using Proximity Ligation Assay

Ryan Arlinghaus, Michiyo Iba, Eliezer Masliah, Mark Cookson, Natalie Landeck

A brain signal linked to disease can be easy to see in large clumps, yet nearly impossible to identify when it is quietly doing its normal work. This study found a way to separate that healthy signal from misleading noise.

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Programmed cell death regulator BAP2 is required for IRE1-mediated unfolded protein response in Arabidopsis 4:06

Programmed cell death regulator BAP2 is required for IRE1-mediated unfolded protein response in Arabidopsis

Noelia Pastor‐Cantizano, Evan Angelos, Cristina Ruberti, Tao Jiang, Xiaoyu Weng, Brandon C. Reagan, Taslima Haque, Thomas Juenger, Federica Brandizzí

When a plant cell is under severe stress, it faces a decision: repair itself or die. This study identifies a protein that helps make that decision, and can push the cell toward either outcome.

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Optimization of PVDF-TrFE Based Electro-Conductive Nanofibers: Morphology and In Vitro Response 2:53

Optimization of PVDF-TrFE Based Electro-Conductive Nanofibers: Morphology and In Vitro Response

William Serrano Garcia, Iriczalli Cruz‐Maya, Anamaris Melendez-Zambrana, Idalia Ramos-Colon, Nicholas J. Pinto, Sylvia Thomas, Vincenzo Guarino

A material can carry electrical charge well and still be a poor choice for living cells. This study found that the most promising fibers were not simply the ones that conducted best.

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Metacommunity structure preserves genome diversity in the presence of gene-specific selective sweeps under moderate rates of horizontal gene transfer 5:35

Metacommunity structure preserves genome diversity in the presence of gene-specific selective sweeps under moderate rates of horizontal gene transfer

Simone Pompei, E. Della Bella, Joshua S. Weitz, Jacopo Grilli, Marco Cosentino Lagomarsino

A useful gene can spread through a microbial community without dragging the rest of the genome along with it. This study suggests that separated habitats help explain how diversity survives that takeover.

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Association between serum polyunsaturated fatty acids and bone mineral density in US adults: NHANES 2011-2014 3:01

Association between serum polyunsaturated fatty acids and bone mineral density in US adults: NHANES 2011-2014

Hao Liang, Chuang Xiong, Yuangang Luo, Jun Zhang, Yanran Huang, Runhan Zhao, Nian Zhou, Zenghui Zhao, Xiaoji Luo

Could the fats circulating in your blood be connected with how strong your bones are? This study found one fat linked with denser bone in some places, but another linked with lower density elsewhere.

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Corrosion of Titanium Electrode Used for Solar Saline Electroflotation 3:20

Corrosion of Titanium Electrode Used for Solar Saline Electroflotation

Felipe M. Galleguillos Madrid, María P. Arancibia-Bravo, Jonathan Cisterna, Álvaro Soliz, Sebastián Salazar-Avalos, B. Guevara, Felipe Araya Sepúlveda, Luis Cáceres

What if sunlight and seawater could help clean up mining, but the salty water slowly eats the machine doing the work? This study finds that a titanium electrode can withstand that challenge better than expected.

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PANoptosis-related genes function as efficient prognostic biomarkers in colon adenocarcinoma 3:35

PANoptosis-related genes function as efficient prognostic biomarkers in colon adenocarcinoma

Yang Liu, Yang Liu, Yizhao Wang, Huijin Feng, Lianjun Ma, Yanqing Liu, Yanqing Liu

When cancer cells die, that event may reveal more than the loss of a cell. It may also reflect how the immune system is responding, and help indicate how a colon cancer patient’s disease could unfold.

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Design, synthesis, and in vitro evaluation of a carbamazepine derivative with antitumor potential in a model of Acute Lymphoblastic Leukemia 3:50

Design, synthesis, and in vitro evaluation of a carbamazepine derivative with antitumor potential in a model of Acute Lymphoblastic Leukemia

Cristian Álvarez-Gómez, Angela Fonseca-Benítez, James Guevara‐Pulido

A medicine already used for other conditions was reshaped into a possible leukemia treatment. In laboratory tests, its redesigned form reduced leukemia-cell survival while showing a more favorable effect on healthy cells.

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Investigating genetic diversity within the most abundant and prevalent non-pathogenic leaf-associated bacteria interacting with Arabidopsis thaliana in natural habitats 5:01

Investigating genetic diversity within the most abundant and prevalent non-pathogenic leaf-associated bacteria interacting with Arabidopsis thaliana in natural habitats

Daniela Ramírez-Sánchez, Chrystel Gibelin‐Viala, Baptiste Mayjonade, Rémi Duflos, Elodie Belmonte, Vincent Pailler, Claudia Bartoli, Sébastien Carrère, Fabienne Vailleau, Fabrice Roux

Two bacteria can be grouped as the same kind, yet carry different genes and make the same plant grow differently. That hidden variation may matter for healthier, more sustainable crops.

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Nurses and Physicians’ Perceptions Regarding the Role of Oncology Clinical Nurse Specialists in an Exploratory Qualitative Study 3:53

Nurses and Physicians’ Perceptions Regarding the Role of Oncology Clinical Nurse Specialists in an Exploratory Qualitative Study

Keren Dopelt, Noam Asna, Mazal Amoyal, Osnat Bashkin

Cancer care is not only about choosing a treatment. Patients and families also need someone to help connect medical decisions, daily problems, and the long stretch after treatment. This study asks whether oncology nurses could fill that missing role in Israel.

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Current state of NK cell-mediated immunotherapy in chronic lymphocytic leukemia 5:22

Current state of NK cell-mediated immunotherapy in chronic lymphocytic leukemia

Zonghan Wang, Wei Li, Hao Dong, Fujun Han

When standard leukemia treatments fall short, the body may already have another weapon: immune cells that can recognize and attack cancer without needing the same target as other immune therapies.

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Non-invasive investigation of Polychromophilus parasite infections in bat populations in Serbia using bat flies 3:37

Non-invasive investigation of Polychromophilus parasite infections in bat populations in Serbia using bat flies

Branka Bajić, Oskar Werb, Ivana Budinski, Jelena Blagojević, Juliane Schaer, Jaap van Schaik

A bat can carry a hidden infection without giving researchers an easy way to check. This study finds that the bat fly riding on its body can act like a tiny, non-invasive warning signal.

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