Open access

Papers, explained

338 open-access papers, free to watch.

Effects of immunogenic cell death-inducing chemotherapeutics on the immune cell activation and tertiary lymphoid structure formation in melanoma

Effects of immunogenic cell death-inducing chemotherapeutics on the immune cell activation and tertiary lymphoid structure formation in melanoma

Hua Zhao, Yu Zhao, Siyuan Zhang, Zhe Wang, Wenwen Yu, Nan Dong, Xuena Yang, Xi‐Ying Zhang, Qian Sun, Xishan Hao, Xiubao Ren

What if a chemotherapy drug did more than slow a tumor? In melanoma-bearing mice, one drug also helped build doorways and meeting places that brought immune cells into the tumor.

Overview In depth

Do different robot appearances change emotion recognition in children with ASD?

Do different robot appearances change emotion recognition in children with ASD?

Maria J. Pinto-Bernal, Sergio D. Sierra M., Marcela Múnera, Diego Casas, Adriana Villa-Moreno, Anselmo Frizera, Martin F. Stoelen, Tony Belpaeme, Carlos A. Cifuentes

A robot can teach children to read emotions, but does its face change what they learn? This study found a striking difference in attention, but not the improvement many people might expect.

Overview In depth

A robust multi-objective optimization algorithm for accurate parameter estimation for solar cell models

A robust multi-objective optimization algorithm for accurate parameter estimation for solar cell models

Manish Kumar Singla, Jyoti Gupta, Mohammed H. Alsharif, Mun-Kyeom Kim, Mohammad Aljaidi, Murodbek Safaraliev

A solar panel can be physically perfect yet mathematically misunderstood. This study finds a way to estimate the hidden numbers inside a panel more accurately, helping models predict how much power it can produce.

Overview In depth

Update on mosquito bite reaction: Itch and hypersensitivity, pathophysiology, prevention, and treatment

Update on mosquito bite reaction: Itch and hypersensitivity, pathophysiology, prevention, and treatment

Ashley Vander Does, Angelina Labib, Gil Yosipovitch

For most people, a mosquito bite is a small nuisance. For some, the same bite can trigger severe swelling, fever, or even a dangerous whole-body reaction, and the familiar itch may involve more than histamine.

Overview In depth

Anti-inflammatory activity of benidipine hydrochloride in LPS-activated mammalian macrophages

Anti-inflammatory activity of benidipine hydrochloride in LPS-activated mammalian macrophages

Hülya Servi, Tanya Beril Korkmaz, Furkan Ayaz

A medicine commonly used for high blood pressure may do more than relax blood vessels. In this study, it also quieted several alarm signals from immune cells when inflammation was already switched on.

Overview In depth

Body movement as a biomarker for use in chronic pain rehabilitation: An embedded analysis of an RCT of a virtual reality solution for adults with chronic pain

Body movement as a biomarker for use in chronic pain rehabilitation: An embedded analysis of an RCT of a virtual reality solution for adults with chronic pain

Sammeli Liikkanen, Mika Mäkinen, Teppo Huttunen, Toni Sarapohja, Carina Stenfors, Christopher Eccleston

Pain cannot be seen directly, but the way a person moves may leave a useful trace. This study asks whether moving faster during virtual-reality rehabilitation can signal that chronic back pain is improving.

Overview In depth

Synthesis vs. salvage of ester- and ether-linked phosphatidylethanolamine in the intracellular protozoan pathogen Toxoplasma gondii

Synthesis vs. salvage of ester- and ether-linked phosphatidylethanolamine in the intracellular protozoan pathogen Toxoplasma gondii

Bingjian Ren, Xiaohan Liang, Jos F. Brouwers, Rosalba Cruz‐Mirón, Bang Shen, Nishith Gupta

A parasite invading human cells has a supply problem: it needs building material for new membranes, but it does not make every kind itself. This study finds it manufactures one form and steals another from its host.

Overview In depth

Bullying prevalence in Pakistan’s educational institutes: Preclusion to the framework for a teacher-led antibullying intervention

Bullying prevalence in Pakistan’s educational institutes: Preclusion to the framework for a teacher-led antibullying intervention

Sohni Siddiqui, Anja Schultze‐Krumbholz

Bullying in Pakistani schools is not only about punches or online posts. Teachers most often notice something quieter: words and social exclusion, and what they see changes with students’ age and where the school is located.

Overview In depth

A high-efficiency elementary network of interchangeable superconducting qubit devices

A high-efficiency elementary network of interchangeable superconducting qubit devices

Michael Mollenhauer, Abdullah Irfan, Xi Cao, Supriya Mandal, Wolfgang Pfaff

What if a quantum computer did not have to be built as one giant, delicate object? This experiment shows that separate quantum devices can be connected by a cable, unplugged, and still exchange information with about one percent loss.

Overview In depth

Resting-state occipito-frontal alpha connectome is linked to differential word learning ability in adult learners

Resting-state occipito-frontal alpha connectome is linked to differential word learning ability in adult learners

Yan Huang, Yao Deng, Xiaoming Jiang, Yiyuan Chen, Tianxin Mao, Yong Xu, Caihong Jiang, Hengyi Rao

Why can one adult learn a new word almost effortlessly while another struggles? This study suggests the answer may partly lie in how two distant parts of the resting brain keep time together.

Overview In depth

Implementation strategies in the Exploration and Preparation phases of a colorectal cancer screening intervention in community health centers

Implementation strategies in the Exploration and Preparation phases of a colorectal cancer screening intervention in community health centers

Renée M. Ferrari, Jennifer Leeman, Alison T. Brenner, Sara Y. Correa, Teri L. Malo, Alexis Moore, Meghan C. O’Leary, Connor M. Randolph, Shana Ratner, Leah Frerichs, Deeonna E. Farr, Seth D. Crockett, Stephanie B. Wheeler, Kristen Hassmiller Lich, Evan Beasley, Michelle Hogsed, Ashley Bland, Claudia Richardson, Mike Newcomer, Daniel S. Reuland

Colorectal cancer screening can save lives, yet the people most likely to be missed are often those with lower incomes or no insurance. This study asked how to make screening fit the places serving them.

Overview In depth

Colostrum Proteins in Protection against Therapy-Induced Injuries in Cancer Chemo- and Radiotherapy: A Comprehensive Review

Colostrum Proteins in Protection against Therapy-Induced Injuries in Cancer Chemo- and Radiotherapy: A Comprehensive Review

Jolanta Artym, Michał Zimecki

Cancer treatment can attack healthy tissue while attacking a tumor. This review asks whether proteins from colostrum, the first milk after birth, could help protect the body without weakening treatment.

Overview In depth