Open access

Papers, explained

338 open-access papers, free to watch.

Administration of ketoprofen in postpartum sows to control the incidence of post-parturient disorders and improve piglet survival rate 4:10

Administration of ketoprofen in postpartum sows to control the incidence of post-parturient disorders and improve piglet survival rate

The first days after birth can decide whether a piglet survives. This study asks whether easing a mother’s pain changes that delicate handoff of early nourishment, and finds a more complicated answer.

Preparation and Characterization of a Novel Self-Healing Transparent Polyimide Film Based on Dynamic Disulfide Bonds 3:44

Preparation and Characterization of a Novel Self-Healing Transparent Polyimide Film Based on Dynamic Disulfide Bonds

A scratch on a flexible screen can threaten the whole device. This study tests a clear plastic film that can close its own scratches when heated, while staying strong and transparent.

Clinical and multimodal imaging features of adult-onset neuronal intranuclear inclusion disease 4:00

Clinical and multimodal imaging features of adult-onset neuronal intranuclear inclusion disease

A rare brain disease can look completely different from one person to the next. But a particular pattern on a brain scan may provide a crucial clue, sometimes before doctors know what they are seeing.

Endotrophin, a fibroblast matrikine, may be a driver of fibroblast activation in fibro-inflammatory diseases 2:54

Endotrophin, a fibroblast matrikine, may be a driver of fibroblast activation in fibro-inflammatory diseases

A small fragment released from the heart’s supporting tissue may do more than mark trouble. It may help push heart cells to build the very scar-like material that makes the heart work poorly.

GMP-compliant, serum-free cultures preserve therapeutic potential of extracellular vesicles from human mesenchymal stromal cells 4:08

GMP-compliant, serum-free cultures preserve therapeutic potential of extracellular vesicles from human mesenchymal stromal cells

Tiny packages released by human cells can help calm the process that scars a liver. But before such treatments reach patients, scientists need a way to make those packages cleanly and consistently.

Prospective Molecular Targets for Natural Killer Cell Immunotherapy against Glioblastoma Multiforme 4:05

Prospective Molecular Targets for Natural Killer Cell Immunotherapy against Glioblastoma Multiforme

Glioblastoma is a devastating brain cancer, and standard treatment has not produced lasting survival gains. This review asks whether the body’s natural killer cells can be directed toward the tumor in several different ways.

KP177R-based visual assay integrating RPA and CRISPR/Cas12a for the detection of African swine fever virus 3:42

KP177R-based visual assay integrating RPA and CRISPR/Cas12a for the detection of African swine fever virus

African swine fever can devastate pig herds, yet the crucial first step is simply knowing where the virus is. This study turns that search into a visible signal that can be read outside a full laboratory.

Spatiotemporal regulation of the bone immune microenvironment via a ‘Zn2+-quercetin’ hierarchical delivery system for bone regeneration 4:27

Spatiotemporal regulation of the bone immune microenvironment via a ‘Zn2+-quercetin’ hierarchical delivery system for bone regeneration

Repairing a large bone gap is not just a construction problem. This study suggests the repair material may also need to coach the immune system, quietly at first, then more strongly as healing unfolds.

Exploring Novel Fungal–Bacterial Consortia for Enhanced Petroleum Hydrocarbon Degradation 3:30

Exploring Novel Fungal–Bacterial Consortia for Enhanced Petroleum Hydrocarbon Degradation

A diesel spill can remain in soil for years. This study found that the strongest cleanup came not from one microbe, but from a carefully matched team of fungi and bacteria working together.

Web-Based Exercise Interventions for Children with Neurodevelopmental Disorders 3:09

Web-Based Exercise Interventions for Children with Neurodevelopmental Disorders

For some children, exercise support can be hard to reach. This review asks whether a screen can bring that support home, and finds encouraging results, but not for every child or every goal.

Automated LVO detection and collateral scoring on CTA using a 3D self-configuring object detection network: a multi-center study 3:07

Automated LVO detection and collateral scoring on CTA using a 3D self-configuring object detection network: a multi-center study

When a major blood vessel in the brain is blocked, every delay can matter. This study asks whether a computer can spot that blockage on a routine scan, and also judge how well blood is finding another route around it.

Behaviour and Microstructural Characteristics of Lime-GGBS-Treated Kaolin Clay Contaminated with Gypsum 4:28

Behaviour and Microstructural Characteristics of Lime-GGBS-Treated Kaolin Clay Contaminated with Gypsum

A road can fail not because its soil is too weak, but because the repair material makes it swell. This study finds a different mixture that strengthens the ground while sharply reducing that dangerous expansion.