Paperi
Open access

Papers, explained

338 open-access papers, free to watch.

Hepatitis B Core Antibody Level: A Surrogate Marker for Host Antiviral Immunity in Chronic Hepatitis B Virus Infections 4:33

Hepatitis B Core Antibody Level: A Surrogate Marker for Host Antiviral Immunity in Chronic Hepatitis B Virus Infections

Yang Shi, Zihan Wang, Shengxiang Ge, Ningshao Xia, Quan Yuan

A routine blood antibody may reveal more than whether hepatitis B was ever present. Its level may act like a dashboard for how strongly the body is fighting the virus, and how likely treatment is to help.

OverviewIn depth

Case report: Extending the spectrum of clinical and molecular findings in FOXC1 haploinsufficiency syndrome 4:30

Case report: Extending the spectrum of clinical and molecular findings in FOXC1 haploinsufficiency syndrome

Alexandra Garza Flores, I. Nordgren, Maria Pettersson, Dora Dias‐Santagata, Daniel Nilsson, Anna Hammarsjö, Anna Lindstrand, Dominyka Batkovskyte, Janey L. Wiggs, David S. Walton, Paula Goldenberg, Jesper Eisfeldt, Angela E. Lin, Ralph S. Lachman, Gen Nishimura, Giedré Grigelioniené

A condition often recognized through the eyes can reach far beyond vision. In two adults, the same missing genetic instruction was linked to glaucoma, unusual bones, loose joints, and problems that became clearer with age.

OverviewIn depth

The effects of substance use on non-communicable diseases among older adults aged 60 and above in the North-eastern States of India 4:23

The effects of substance use on non-communicable diseases among older adults aged 60 and above in the North-eastern States of India

Sasanka Boro, Nandita Saikia

For older adults in North-eastern India, tobacco and alcohol are not just habits carried into later life. This study finds they are closely tied to several chronic illnesses, with one especially striking link to cancer.

OverviewIn depth

Antibiotic resistance, bacterial transmission and improved prediction of bacterial infection in patients with antibody deficiency 3:19

Antibiotic resistance, bacterial transmission and improved prediction of bacterial infection in patients with antibody deficiency

Sylvia Rofael, Clara Leboreiro-Babe, Mehmet Davrandi, Alexandra L Kondratiuk, Leanne Cleaver, Naseem Ahmed, Claire Atkinson, Timothy D. McHugh, David M. Lowe

For people whose immune defenses are already weakened, antibiotics can be lifesaving. But this study finds that the bacteria living in their airways may already resist many of those drugs, and may even pass resistance between patients.

OverviewIn depth

Competition for Nitrogen Resources: An Explanation of the Effects of a Bioprotective Strain Metschnikowia pulcherrima on the Growth of Hanseniaspora Genus in Oenology 4:21

Competition for Nitrogen Resources: An Explanation of the Effects of a Bioprotective Strain Metschnikowia pulcherrima on the Growth of Hanseniaspora Genus in Oenology

Maëlys Puyo, Léa Scalabrino, Rémy Romanet, Scott Simonin, Géraldine Klein, Hervé Alexandre, Raphaëlle Tourdot‐Maréchal

A natural yeast added to grape juice can protect the future wine from unwanted microbes, but only against some of them. The surprising reason may be a struggle over the same basic food: nitrogen.

OverviewIn depth

Diamine Groups on the Surface of Silica Particles as Complex-Forming Linkers for Metal Cations 4:14

Diamine Groups on the Surface of Silica Particles as Complex-Forming Linkers for Metal Cations

Veronika Tomina, N. V. Stolyarchuk, Olha Semeshko, Mariusz Barczak, Inna Melnyk

Cleaning industrial water is not only about removing toxic metals. It can also recover valuable metals for reuse. This study finds that a particle with more metal-catching groups is not always the better catcher.

OverviewIn depth

Ten-Year Trends in Psychotropic Prescribing and Polypharmacy in Australian General Practice Patients with and without Dementia 3:43

Ten-Year Trends in Psychotropic Prescribing and Polypharmacy in Australian General Practice Patients with and without Dementia

Woldesellassie M. Bezabhe, Jan Radford, Mohammed S. Salahudeen, Ivan Bindoff, Tristan Ling, Peter Gee, Barbara C. Wimmer, Gregory M. Peterson

For people with dementia, medicines aimed at distressing behaviour became less common over a decade, but taking several of these medicines at once still affected almost one person in five by the end.

OverviewIn depth

Immunotherapy or targeted therapy: What will be the future treatment for anaplastic thyroid carcinoma? 3:55

Immunotherapy or targeted therapy: What will be the future treatment for anaplastic thyroid carcinoma?

Xiaoni Gao, Chengcheng Hong, Yang Xie, Xiangtai Zeng

A rare thyroid cancer causes more than half of all deaths from thyroid cancer, yet makes up only a small fraction of cases. This review asks whether the answer is to target the cancer’s weak spots, awaken the immune system, or combine both.

OverviewIn depth

Mental stress objective screening for workers using urinary neurotransmitters 3:25

Mental stress objective screening for workers using urinary neurotransmitters

Kazuhiro Tanabe, Asaka Yokota

Stress can be affecting a worker before they call themselves unwell. This study asks whether a urine sample could reveal that hidden strain early enough to act on it.

OverviewIn depth

Thermal Stability and Flame Retardancy of Rigid Polyurethane Foam Composites Filled with Phase-Change Microcapsule 4:54

Thermal Stability and Flame Retardancy of Rigid Polyurethane Foam Composites Filled with Phase-Change Microcapsule

Qing Cao, Qing Cao, Q. Cao, Q. Cao, Lujie Zhou, Kai Yu

Rigid polyurethane foam is useful in cars, buildings, mining and aerospace, but it burns easily, releases toxic gases, and can trap enough heat to help start a fire. This study asks whether the same material can be made to absorb heat and slow flames.

OverviewIn depth

An Authentication Survey on Retail Seafood Products Sold on the Bulgarian Market Underlines the Need for Upgrading the Traceability System 4:33

An Authentication Survey on Retail Seafood Products Sold on the Bulgarian Market Underlines the Need for Upgrading the Traceability System

Lara Tinacci, Deyan Stratev, Mariyana Strateva, G. Zhelyazkov, Ralica Kyuchukova, Andrea Armani

A seafood label can promise one species while the food inside is another. In Bulgaria, a broad check of shop-bought seafood found that this was not a rare mistake, but a problem affecting about one product in nine.

OverviewIn depth

Synthesis of L-Ornithine- and L-Glutamine-Linked PLGAs as Biodegradable Polymers 4:10

Synthesis of L-Ornithine- and L-Glutamine-Linked PLGAs as Biodegradable Polymers

Gülce Taşkor Önel

A familiar medical plastic can be redesigned with parts borrowed from the human body, and that small change makes it become friendlier to water and break down faster. The surprising part is how useful that controlled breakdown could be.

OverviewIn depth