Medicine

50 open-access papers in Medicine, free to watch.

Body movement as a biomarker for use in chronic pain rehabilitation: An embedded analysis of an RCT of a virtual reality solution for adults with chronic pain

Body movement as a biomarker for use in chronic pain rehabilitation: An embedded analysis of an RCT of a virtual reality solution for adults with chronic pain

Sammeli Liikkanen, Mika Mäkinen, Teppo Huttunen, Toni Sarapohja, Carina Stenfors, Christopher Eccleston

Pain cannot be seen directly, but the way a person moves may leave a useful trace. This study asks whether moving faster during virtual-reality rehabilitation can signal that chronic back pain is improving.

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Objective analysis of partial three-dimensional rotator cuff muscle volume and fat infiltration across ages and sex from clinical MRI scans

Objective analysis of partial three-dimensional rotator cuff muscle volume and fat infiltration across ages and sex from clinical MRI scans

Lara Riem, Silvia S. Blemker, Olivia DuCharme, Elizabeth B. Leitch, Matthew Cousins, Ivan J. Antosh, Mikalyn Defoor, Andrew J. Sheean, Brian C. Werner

A shoulder MRI often captures only part of the shoulder blade. This study finds that partial images can still reveal meaningful three-dimensional changes in the muscles that help lift and stabilize the arm.

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The Association of Plasma Homocysteine Concentrations with a 10-Year Risk of All-Cause and Cardiovascular Mortality in a Community-Based Chinese Population

The Association of Plasma Homocysteine Concentrations with a 10-Year Risk of All-Cause and Cardiovascular Mortality in a Community-Based Chinese Population

Zhe Liang, Kaiyin Li, Hongyu Chen, Jia Jia, Jianping Li, Yong Huo, Fangfang Fan, Yan Zhang

A substance in the blood was linked with a higher chance of dying over the next decade, but the strength of that link depended partly on a person’s inherited biology.

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Performance of a safe and dignified burial intervention during an Ebola epidemic in the eastern Democratic Republic of the Congo, 2018–2019

Performance of a safe and dignified burial intervention during an Ebola epidemic in the eastern Democratic Republic of the Congo, 2018–2019

Abdihamid Warsame, Gwendolen Eamer, Alaria Kai, Lucia Robles Dios, Hana Rohan, Patrick Keating, Jacques Katshishi, Francesco Checchi

During an Ebola outbreak, a funeral can protect a community, or spread infection. This study found that getting a burial team there quickly was possible, but safety also depended on whether families and neighbours trusted the response.

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Endotrophin, a fibroblast matrikine, may be a driver of fibroblast activation in fibro-inflammatory diseases

Endotrophin, a fibroblast matrikine, may be a driver of fibroblast activation in fibro-inflammatory diseases

Alexander Lynge Reese‐Petersen, Federica Genovese, Lei Zhao, G. Banks, David A. Gordon, M.A. Karsdal

A small fragment released from the heart’s supporting tissue may do more than mark trouble. It may help push heart cells to build the very scar-like material that makes the heart work poorly.

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Automated LVO detection and collateral scoring on CTA using a 3D self-configuring object detection network: a multi-center study

Automated LVO detection and collateral scoring on CTA using a 3D self-configuring object detection network: a multi-center study

Ömer Bağcılar, Deniz Alış, Ceren Aliş, Mustafa Ege Şeker, Mert Yergin, Ahmet Üstündağ, Emil Hikmet, Alperen Tezcan, Gökhan Polat, Ahmet Tuğrul Akkuş, Fatih Alper, Murat Velioğlu, Ömer Yıldız, Hakan Hatem Selçuk, İlkay Öksüz, Osman Kızılkılıç, Ercan Karaarslan

When a major blood vessel in the brain is blocked, every delay can matter. This study asks whether a computer can spot that blockage on a routine scan, and also judge how well blood is finding another route around it.

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Moschus ameliorates glutamate-induced cellular damage by regulating autophagy and apoptosis pathway

Moschus ameliorates glutamate-induced cellular damage by regulating autophagy and apoptosis pathway

Danni Xie, Caiyou Song, Tao Qin, Zhenwei Zhai, Jie Cai, Jiyan Dai, Tao Sun, Ying Xu

A traditional animal medicine appeared to protect nerve-like cells from a chemical stress linked to brain damage. But the important clue was not simply that more cells survived, it was how the cells’ own cleanup and self-destruction systems changed.

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Understanding general practitioner and pharmacist preferences for pharmacogenetic testing in primary care: a discrete choice experiment

Understanding general practitioner and pharmacist preferences for pharmacogenetic testing in primary care: a discrete choice experiment

John McDermott, Videha Sharma, Glenda M. Beaman, Jessica Keen, William G. Newman, Paul Wilson, Katherine Payne, Stuart Wright

A genetic test can promise safer, more effective prescribing, but this study found that whether clinicians use it may depend just as much on how the service is built as on the test itself.

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Translation and Validation of the City Birth Trauma Scale With Lithuanian Postpartum Women: Findings and Initial Results

Translation and Validation of the City Birth Trauma Scale With Lithuanian Postpartum Women: Findings and Initial Results

Olga Riklikienė, Gabija Jarašiūnaitė–Fedosejeva, Ernesta Sakalauskienė, Žydrūnė Luneckaitė, Susan Ayers

Childbirth is expected to be one of life’s most meaningful events, yet for some women it becomes psychologically traumatic. This study asks a practical question: can a short questionnaire reliably recognize that hidden distress in Lithuania?

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Specific Detection of Physiological S129 Phosphorylated α-Synuclein in Tissue Using Proximity Ligation Assay

Specific Detection of Physiological S129 Phosphorylated α-Synuclein in Tissue Using Proximity Ligation Assay

Ryan Arlinghaus, Michiyo Iba, Eliezer Masliah, Mark Cookson, Natalie Landeck

A brain signal linked to disease can be easy to see in large clumps, yet nearly impossible to identify when it is quietly doing its normal work. This study found a way to separate that healthy signal from misleading noise.

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PANoptosis-related genes function as efficient prognostic biomarkers in colon adenocarcinoma

PANoptosis-related genes function as efficient prognostic biomarkers in colon adenocarcinoma

Yang Liu, Yang Liu, Yizhao Wang, Huijin Feng, Lianjun Ma, Yanqing Liu, Yanqing Liu

When cancer cells die, that event may reveal more than the loss of a cell. It may also reflect how the immune system is responding, and help indicate how a colon cancer patient’s disease could unfold.

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Defining the ferroptotic phenotype of beta cells in type 1 diabetes and its inhibition as a potential antidiabetic strategy

Defining the ferroptotic phenotype of beta cells in type 1 diabetes and its inhibition as a potential antidiabetic strategy

Milica Markelić, Ana Stančić, Tamara Saksida, Ilijana Grigorov, Dragica Mićanović, Ksenija Veličković, Vesna Martinović, Nevena Savic, Andjelija Gudelj, Vesna Otašević

In type 1 diabetes, insulin-making cells may not only be attacked by the immune system, they may also be destroyed by a chain reaction involving iron and damaged fats. Blocking that reaction helped preserve signs of pancreatic health in diabetic mice.

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