Medicine

50 open-access papers in Medicine, free to watch.

Real-time PCR detection of mixed Plasmodium ovale curtisi and wallikeri infections in human and mosquito hosts

Real-time PCR detection of mixed Plasmodium ovale curtisi and wallikeri infections in human and mosquito hosts

Varun R. Potlapalli, Meredith Muller, Billy Ngasala, Innocent Mbulli Ali, Yu Bin Na, Danielle R. Williams, Oksana Kharabora, Srijana Chhetri, Mei S. Liu, Kelly Carey-Ewend, Feng‐Chang Lin, Derrick K. Mathias, Brian B. Tarimo, Jonathan J. Juliano, Jonathan B. Parr, Jessica T. Lin

A malaria infection that looks like one may actually contain two closely related species. The surprise is that mosquitoes revealed mixed infections far more often than human blood tests did.

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Plitidepsin in adult patients with COVID-19 requiring hospital admission: A long-term follow-up analysis

Plitidepsin in adult patients with COVID-19 requiring hospital admission: A long-term follow-up analysis

José Felipe Varona, Pedro Landete, Roger Paredes, Roberto Vates, Miguel Torralba, Pablo Guisado‐Vasco, Lourdes Porras, Patricia Muñóz, Paloma Gijón, Julio Ancochea, Elena María Saiz, Fernanda Salazar Meira, José María Jimeno, Jose Antonio Lopez-Martin, Vicente Estrada

COVID-19 can end in the hospital and still keep changing a person’s life months later. This follow-up asks whether people treated with plitidepsin remained well over the longer term.

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SARS-Cov-2 incubation period according to vaccination status during the fifth COVID-19 wave in a tertiary-care center in Spain: a cohort study

SARS-Cov-2 incubation period according to vaccination status during the fifth COVID-19 wave in a tertiary-care center in Spain: a cohort study

Jordi Cortés Martínez, Daewoo Pak, Gabriela Abelenda-Alonso, Klaus Langohr, Jing Ning, Alexander Rombauts, Mireia Colom, Yu Shen, Guadalupe Gómez Melis

Vaccination protected people from severe COVID, but did it also change the hidden countdown between infection and symptoms? This study found a more complicated answer than a simple yes or no.

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Impact of neurofibromatosis type 1 with plexiform neurofibromas on the health-related quality of life and work productivity of adult patients and caregivers in the UK: a cross-sectional survey

Impact of neurofibromatosis type 1 with plexiform neurofibromas on the health-related quality of life and work productivity of adult patients and caregivers in the UK: a cross-sectional survey

Hyun Kyoo Yoo, Alex Porteous, Alvin Wei Tian Ng, Keval Haria, Annabel Griffiths, Andrew J. Lloyd, Xiaoqin Yang, Gbenga Kazeem, Volkan Barut

A condition affecting nerves can reshape daily life for both the person who has it and the family member who helps care for them. This survey found the burden reaches far beyond the tumour itself.

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Can heat conditions affect the heart rate responses, perception of effort, and technical performance of young male football players during small-sided games? a comparative study

Can heat conditions affect the heart rate responses, perception of effort, and technical performance of young male football players during small-sided games? a comparative study

ZhiHui Kang, Z. Chen, G. B. Liu

A hot football session can make young players’ hearts race and effort feel harder, yet the clearest sign may be quieter: they complete fewer passes. The surprising part is what heat does not change.

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Contemporary national outcomes of hyperbaric oxygen therapy in necrotizing soft tissue infections

Contemporary national outcomes of hyperbaric oxygen therapy in necrotizing soft tissue infections

William Toppen, Nam Yong Cho, Sohail Sareh, Anders Kjellberg, Anthony J. Medak, Peyman Benharash, Peter Lindholm

A fast-moving infection can destroy skin, muscle, and deeper tissue, sometimes costing a person a limb or their life. This study asks whether breathing oxygen under pressure may improve those odds.

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Effects of cervical rotatory manipulation on the cervical spinal cord complex with ossification of the posterior longitudinal ligament in the vertebral canal: A finite element study

Effects of cervical rotatory manipulation on the cervical spinal cord complex with ossification of the posterior longitudinal ligament in the vertebral canal: A finite element study

Xue Fan, Hao Deng, Zujiang Chen, Han Seok Yang, Yikai Li, Shiguo Yuan, Nansheng Zheng, Meixiong Chen

A neck movement that may feel routine can become a much riskier event when bone has narrowed the space around the spinal cord. This study found that twisting the neck under those conditions can sharply raise mechanical stress.

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Life satisfaction 18 months and 10 years following spinal cord injury: results from a New Zealand prospective cohort study

Life satisfaction 18 months and 10 years following spinal cord injury: results from a New Zealand prospective cohort study

Ruby Dixon, Sarah Derrett, Ari Samaranayaka, Helen Harcombe, Emma Wyeth, Carolyn Beaver, Martin J. Sullivan

A spinal cord injury can change almost every part of daily life. Yet this study found something many people may not expect: satisfaction with life was more common ten years later than it was eighteen months after the injury.

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Mechanism of action of nadofaragene firadenovec-vncg

Mechanism of action of nadofaragene firadenovec-vncg

Vikram M. Narayan, Joshua J. Meeks, Jørn S. Jakobsen, Neal D. Shore, Grannum R. Sant, Badrinath R. Konety

When bladder cancer returns despite standard treatment, preserving the bladder can become difficult. This therapy takes a gene into bladder cells so they keep making a signal that can attack the tumor directly and call immune defenses to the scene.

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The inflammatory prognostic index as a potential predictor of prognosis in metastatic gastric cancer

The inflammatory prognostic index as a potential predictor of prognosis in metastatic gastric cancer

Ahmet Özveren, Atike Pınar Erdoğan, Ferhat Ekinci

When stomach cancer has already spread, doctors need clues about how the illness may unfold. This study suggests that information already present in a routine blood test could help separate higher-risk patients from lower-risk patients.

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Effects of immunogenic cell death-inducing chemotherapeutics on the immune cell activation and tertiary lymphoid structure formation in melanoma

Effects of immunogenic cell death-inducing chemotherapeutics on the immune cell activation and tertiary lymphoid structure formation in melanoma

Hua Zhao, Yu Zhao, Siyuan Zhang, Zhe Wang, Wenwen Yu, Nan Dong, Xuena Yang, Xi‐Ying Zhang, Qian Sun, Xishan Hao, Xiubao Ren

What if a chemotherapy drug did more than slow a tumor? In melanoma-bearing mice, one drug also helped build doorways and meeting places that brought immune cells into the tumor.

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Update on mosquito bite reaction: Itch and hypersensitivity, pathophysiology, prevention, and treatment

Update on mosquito bite reaction: Itch and hypersensitivity, pathophysiology, prevention, and treatment

Ashley Vander Does, Angelina Labib, Gil Yosipovitch

For most people, a mosquito bite is a small nuisance. For some, the same bite can trigger severe swelling, fever, or even a dangerous whole-body reaction, and the familiar itch may involve more than histamine.

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